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Nareg RoubinianNareg Roubinian, MD, MPHTM

Current Positions:

  • Assistant Clinical Investigator, BSRI
  • Assistant Adjust Professor, UCSF Department of Laboratory Medicine

 

Contact Information:
270 Masonic Ave.
San Francisco, CA 94118
Phone: (415) 923-5771 x655
Fax: (415) 901-0733
Email: nroubinian@bloodsystems.org

 

Download a scientific summary [pdf file]

Download a curriculum vitae [pdf file]

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Education:

  • B.S., Molecular Biology & Integrative Biology, University of California at Berkeley
  • M.D., College of Medicine, University of Vermont
  • MPHTM, School of Public Health & Tropical Medicine, Tulane University

Training / Prior Appointments:

  • Residency in Internal Medicine, Barnes Jewish Hospital, St. Louis, Washington University
  • Pulmonary & Critical Care Medicine Fellow, University of California San Francisco
  • Assistant Clinical Professor, University of California San Francisco

Research Interests:

  • Trends in blood utilization and recipient outcomes
  • Predictive models of blood product utilization
  • Clinical & laboratory predictors of pulmonary transfusion reactions

Current research:

Transfusion Recipient Outcomes
As part of a Recipient Epidemiology and Donor Study-III (REDS-III) collaboration with the Kaiser Permanente Northern California Division of Research (KPNC-DOR), we are studying the epidemiology of blood transfusion in hospitalized patients. Kaiser Permanente has an integrated health care delivery system with all information systems linked by common medical record, and the Division of Research has developed and validated risk adjustment methodologies that provide opportunities to control for indication bias in our study of transfusion recipients. Current efforts are focused on modeling red blood cell transfusion events to better understand temporal changes in clinical transfusion practice.

Pulmonary Transfusion Reactions
The Severe Transfusion Reactions and Pulmonary Edema (STRIPE) study within REDS-III focuses on risk factors and outcomes of patients with severe transfusion reactions. This prospective multicenter case-control study will utilize an automated hypoxemia alert system to better characterize the prevalence of transfusion-related acute lung injury (TRALI) and transfusion associated circulatory overload (TACO) within hospitalized patients. In addition to clinical predictors, we will examine the role of cardiac biomarkers in identifying individuals at highest risk of developing a transfusion-related pulmonary complication and develop algorithms to distinguish the various associated clinical syndromes.

Publications:

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